At JADED, our specialized Doctors of Physical Therapy have the ability to utilize the many great anti-inflammatory properties of CBD creams while performing high level manual therapy and myofascial manipulation to return our clients to the most optimal potential of health and wellness.
CBD is a powerful anti-inflammatory molecule. Thus, it has the potential to help prevent and treat many of the diseases that have been linked to inflammatory processes. CBD appears to exert its strongest anti-inflammatory actions through its actions at the CB2 receptor and the TRP family of receptors.
CBD also exerts strong anti-inflammatory actions by blocking the activity of two enzymes that play a role in inflammation – cyclooxygenase-2 (COX-2) and 5-lipoxygenase (LOX-5). COX-2 is an enzyme that results in the production of prostaglandins, pro-inflammatory molecules. COX-2 is the target of many NSAIDs, including aspirin. LOX-5 is an enzyme that results in the production of leukotrienes, also pro-inflammatory molecules. CBD can inhibit both COX-2 and LOX-5, giving it powerful anti-inflammatory properties. In fact, CBD can be several hundred times more potent than aspirin at reducing inflammation.
CBD has also been shown to be able reduce levels of inflammatory cytokines, most notably IL-1beta, IL-6, and IFN-beta. The continued circulation of cytokines during chronic inflammation is a major contributor to the pathology of many disorders, which is why CBD’s ability to reduce cytokine levels gives it so much therapeutic potential.
All in all, there is abundant evidence for CBD’s role as a power anti-inflammatory compound. Since inflammation is now understood to be an underlying factor in many disorders, this makes CBD a potential therapeutic compound for a wide range of ailments.